Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Synthesis of peptide-siRNA conjugates via internal sulfonylphosphoramidate modifications and evaluation of their in vitro activity.

Smidt, Jakob Melgaard; Lykke, Lennart; Stidsen, Carsten Enggaard; Pristovsek, Nusa; Gothelf, Kurt V.

Nucleic Acids Res ; 52(1): 49-58, 2024 Jan 11.

Artigo em Inglês | MEDLINE | ID: mdl-37971296

2.

Reversible Protection and Targeted Delivery of DNA Origami with a Disulfide-Containing Cationic Polymer.

Youssef, Sarah; Tsang, Emily; Samanta, Anirban; Kumar, Vipin; Gothelf, Kurt V.

Small ; 20(10): e2301058, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-37916910

3.

An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation.

Dinesen, Anders; Andersen, Veronica L; Elkhashab, Marwa; Pilati, Diego; Bech, Pernille; Fuchs, Elisabeth; Samuelsen, Torbjørn R; Winther, Alexander; Cai, Yunpeng; Märcher, Anders; Wall, Archie; Omer, Marjan; Nielsen, Jesper S; Chudasama, Vijay; Baker, James R; Gothelf, Kurt V; Wengel, Jesper; Kjems, Jørgen; Howard, Kenneth A.

Bioconjug Chem ; 35(2): 214-222, 2024 02 21.

Artigo em Inglês | MEDLINE | ID: mdl-38231391

4.

Conjugation of chemical handles and functional moieties to DNA during solid phase synthesis with sulfonyl azides.

Santorelli, Angel; Gothelf, Kurt V.

Nucleic Acids Res ; 50(13): 7235-7246, 2022 07 22.

Artigo em Inglês | MEDLINE | ID: mdl-35801866

5.

Protein-Templated Reactions Using DNA-Antibody Conjugates.

Baranda Pellejero, Lorena; Nijenhuis, Minke A D; Ricci, Francesco; Gothelf, Kurt V.

Small ; 19(13): e2200971, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-35344264

6.

Diligent Design Enables Antibody-ASO Conjugates with Optimal Pharmacokinetic Properties.

Sela, Tatjana; Mansø, Mads; Siegel, Michel; Marban-Doran, Céline; Ducret, Axel; Niewöhner, Jens; Ravn, Jacob; Martin, Rainer E; Sommer, Annika; Lohmann, Sabine; Krippendorff, Ben-Fillippo; Ladefoged, Mette; Indlekofer, Annette; Quaiser, Tom; Bueddefeld, Florian; Koller, Erich; Mohamed, Mohamed Y; Oelschlaegel, Tobias; Gothelf, Kurt V; Hofer, Kerstin; Schumacher, Felix F.

Bioconjug Chem ; 34(11): 2096-2111, 2023 11 15.

Artigo em Inglês | MEDLINE | ID: mdl-37916986

7.

Insertion of Chemical Handles into the Backbone of DNA during Solid-Phase Synthesis by Oxidative Coupling of Amines to Phosphites.

Hansen, Rikke A; Märcher, Anders; Pedersen, Kristian Nørgaard; Gothelf, Kurt V.

Angew Chem Int Ed Engl ; 62(26): e202305373, 2023 06 26.

Artigo em Inglês | MEDLINE | ID: mdl-37119479

8.

Automated Solid-Phase Oligo(disulfide) Synthesis.

Frandsen, Martin; El-Chami, Kassem; Palmfeldt, Johan; Melgaard Smidt, Jakob; Langballe, Maja E T; Sandahl, Alexander; Gothelf, Kurt V.

Angew Chem Int Ed Engl ; 62(23): e202303170, 2023 06 05.

Artigo em Inglês | MEDLINE | ID: mdl-37005223

9.

Chemical Conjugation to Less Targeted Proteinogenic Amino Acids.

Kjaersgaard, Nanna L; Nielsen, Thorbjørn B; Gothelf, Kurt V.

Chembiochem ; 23(19): e202200245, 2022 10 06.

Artigo em Inglês | MEDLINE | ID: mdl-35781760

10.

One-Step Conversion of NHS Esters to Reagents for Site-Directed Labeling of IgG Antibodies.

Hansen, Rikke A; Märcher, Anders; Gothelf, Kurt V.

Bioconjug Chem ; 33(10): 1811-1817, 2022 10 19.

Artigo em Inglês | MEDLINE | ID: mdl-36202104

11.

Preparation of Maleimide-Modified Oligonucleotides from the Corresponding Amines Using N-Methoxycarbonylmaleimide.

Kjærsgaard, Nanna L; Hansen, Rikke A; Gothelf, Kurt V.

Bioconjug Chem ; 33(7): 1254-1260, 2022 07 20.

Artigo em Inglês | MEDLINE | ID: mdl-35816757

12.

Albumin Biomolecular Drug Designs Stabilized through Improved Thiol Conjugation and a Modular Locked Nucleic Acid Functionalized Assembly.

Dinesen, Anders; Winther, Alexander; Wall, Archie; Märcher, Anders; Palmfeldt, Johan; Chudasama, Vijay; Wengel, Jesper; Gothelf, Kurt V; Baker, James R; Howard, Kenneth A.

Bioconjug Chem ; 33(2): 333-342, 2022 02 16.

Artigo em Inglês | MEDLINE | ID: mdl-35129956

13.

Functionalized Acyclic (l)-Threoninol Nucleic Acid Four-Way Junction with High Stability In Vitro and In Vivo.

Märcher, Anders; Kumar, Vipin; Andersen, Veronica L; El-Chami, Kassem; Nguyen, Thuy J D; Skaanning, Mads K; Rudnik-Jansen, Imke; Nielsen, Jesper S; Howard, Kenneth A; Kjems, Jørgen; Gothelf, Kurt V.

Angew Chem Int Ed Engl ; 61(24): e202115275, 2022 06 13.

Artigo em Inglês | MEDLINE | ID: mdl-35352451

14.

Chemistries for DNA Nanotechnology.

Madsen, Mikael; Gothelf, Kurt V.

Chem Rev ; 119(10): 6384-6458, 2019 05 22.

Artigo em Inglês | MEDLINE | ID: mdl-30714731

15.

A Wireframe DNA Cube: Antibody Conjugate for Targeted Delivery of Multiple Copies of Monomethyl AuristatinâE.

Märcher, Anders; Nijenhuis, Minke A D; Gothelf, Kurt V.

Angew Chem Int Ed Engl ; 60(40): 21691-21696, 2021 09 27.

Artigo em Inglês | MEDLINE | ID: mdl-34309988

16.

A Reagent for Amine-Directed Conjugation to IgG1 Antibodies.

Märcher, Anders; Palmfeldt, Johan; Nisavic, Marija; Gothelf, Kurt V.

Angew Chem Int Ed Engl ; 60(12): 6539-6544, 2021 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-33306206

17.

Two-Dimensional Coordination Networks from Cyclic Dipeptides.

Guo, Yuanyuan; Nuermaimaiti, Ajiguli; Kjeldsen, Niels Due; Gothelf, Kurt V; Linderoth, Trolle R.

J Am Chem Soc ; 142(47): 19814-19818, 2020 11 25.

Artigo em Inglês | MEDLINE | ID: mdl-33179492

18.

Introduction of an Aldehyde Handle on Nanobodies by Affinity-Guided Labeling.

Mortensen, Michael R; Skovsgaard, Mikkel B; Märcher, Anders; Andersen, Veronica L; Palmfeldt, Johan; Nielsen, Thorbjørn B; Tørring, Thomas; Laursen, Nick S; Andersen, Kasper R; Kjems, Jørgen; Gothelf, Kurt V.

Bioconjug Chem ; 31(5): 1295-1300, 2020 05 20.

Artigo em Inglês | MEDLINE | ID: mdl-32320218

19.

Disulphide-mediated site-directed modification of proteins.

Nielsen, Thorbjørn; Märcher, Anders; Drobnáková, Zuzana; Hucko, Michal; Stengl, Milan; Balsánek, Vojtech; Wiberg, Charlotte; Nielsen, Per F; Nielsen, Thomas E; Gothelf, Kurt V; Cló, Emiliano.

Org Biomol Chem ; 18(25): 4717-4722, 2020 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-32525502

20.

Considerations on Probe Design for Affinity-Guided Protein Conjugation.

Mortensen, Michael R; Skovsgaard, Mikkel B; Gothelf, Kurt V.

Chembiochem ; 20(21): 2711-2728, 2019 11 04.

Artigo em Inglês | MEDLINE | ID: mdl-30983114

BVS Doenças Infecciosas e Parasitárias

Informação e Conhecimento para a Saúde

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar: